Inappropriate combination of warfarin and aspirin

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Inappropriate combination of warfarin and aspirin

OBJECTIVE A combination of warfarin and aspirin is associated with increased bleeding compared with warfarin monotherapy. The aim of the study was to investigate the incidence and appropriateness of the combination of warfarin and aspirin in patients with atrial fibrillation (AF) or mechanical heart valve (MHV). METHODS This cross-sectional study included consecutive patients with AF or MHV o...

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Effects of fixed low-dose warfarin, aspirin-warfarin combination therapy, and dose-adjusted warfarin on thrombogenesis in chronic atrial fibrillation.

BACKGROUND AND PURPOSE Recent clinical trials have established that adjusted-dose warfarin (international normalized ratio [INR] 2.0 to 3.0) is highly effective in the reduction of ischemic stroke in patients with nonvalvular atrial fibrillation (AF). We hypothesized that the introduction of fixed low-dose warfarin alone or in combination with aspirin (300 mg) could normalize hemostatic markers...

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Warfarin Versus Warfarin and Aspirin in Atrial Fibrillation

Background Anticoagulation with warfarin is an important therapy for preventing strokes in patients with atrial fibrillation (AF). Physicians often combine warfarin with aspirin despite evidence for increased bleeding. We investigated the hemorrhagic outcomes related to the differential management of AF with warfarin alone versus combination therapy. Methods and Results This retrospective cohor...

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Does the combination of warfarin and aspirin have a place in secondary stroke prevention? No.

The role of combination therapy, whether antiplatelet or antithrombotic, in secondary stroke prevention is controversial. The only widely accepted combination therapy is clopidogrel plus aspirin in patients with coronary, carotid, or intracranial artery stents. The duration of combination antiplatelet therapy in stent patients is, however, controversial, with a minimum of 3 months used in most ...

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Aspirin and warfarin therapy in oculoplastic surgery.

BACKGROUND/AIMS There are no nationally agreed guidelines on preoperative management of patients who are on aspirin or warfarin therapy. There is considerable evidence that complication rates in anticoagulated patients are low whereas there are higher rates of thromboembolic complications in those whose therapy is manipulated. This survey aimed to establish oculoplastic specialist and non-speci...

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ژورنال

عنوان ژورنال: The Anatolian Journal of Cardiology

سال: 2015

ISSN: 2149-2263,2149-2271

DOI: 10.5152/akd.2015.6050